The idea here is that there are parallel Great Wheels out there, all different than the others. Sigil might be different as well, and perhaps there is no Lady of Pain or perhaps there is another guardian of the city or perhaps She was killed eons ago and Sigil is a smoking wreck.
In whatever format you like, feel free to post some ideas of alternative Wheels, factions of the Metaverse (all the Wheels taken together), personalities for metaversal characters, items, places, etc.
My first example will follow below.
edit: Probably best to refer to "our" Multiverse as "Multiverse Prime".